Laval University Laval University
Research Chair on Primary Progressive Aphasias - Lemaire Family Foundation

Nonfluent/Agrammatic Primary Progressive Aphasia

In this variant, people notice slow and effortful speech, as if there is difficulty getting words out.

What are the diagnostic features?

At least one feature among the following:

  1. Agrammatism in language production (grammar or syntax errors, leading to telegraphic speech in severe cases)

  2. Apraxia of speech (motor speech disorder affecting the planning and sequencing of speech sound movements and leading to a hesitant and effortful speech with speech sound errors)

At least two features among the following:

  1. Impaired comprehension of syntactically complex sentences (example: The dog is followed by the girl; It is the girl that the dog follows)

  2. Spared comprehension of single words

  3. Spared object knowledge

Diagnostic features based on Gorno-Tempini et al., 2011

Videos courtesy of Dr Marilu Gorno-Tempini's team at
University of San Francisco (California), Memory and Aging Center

Testimonial

Mrs. Laforest's experience with the nonfluent/agrammatic variant of PPA

Resources:

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